Molecule Details
InChIKeyMPXAEYSGFKRDQM-UHFFFAOYSA-N
Compound Name3-(4-(2-Hydroxypropan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(2H)-one
Canonical SMILESCc1ccc2c(=O)[nH]c(-c3ccc(C(C)(C)O)cc3)cn12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Homologous
Avg pChEMBL7.37
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
O95271 TNKS Homo sapiens Human PF00023 PF12796 PF00644 PF07647 9.2 IC50 ChEMBL;BindingDB
Q9H2K2 TNKS2 Homo sapiens Human PF00023 PF12796 PF13637 PF00644 PF07647 9.1 IC50 ChEMBL;BindingDB
Q9NR21 PARP11 Homo sapiens Human PF00644 PF02825 7.2 IC50 ChEMBL;BindingDB
Q9Y6F1 PARP3 Homo sapiens Human PF00644 PF02877 PF05406 7.0 IC50 ChEMBL;BindingDB
Q9UGN5 PARP2 Homo sapiens Human PF00644 PF02877 PF05406 6.7 IC50 ChEMBL;BindingDB
Q7Z3E1 TIPARP Homo sapiens Human PF00644 6.5 IC50 ChEMBL;BindingDB
P09874 PARP1 Homo sapiens Human PF00533 PF21728 PF00644 PF02877 PF05406 PF00645 PF08063 6.0 IC50 ChEMBL;BindingDB