N-(1-azabicyclo[2.2.2]octan-3-yl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide

InChIKey	`MPIBCTUFGUTVSG-UHFFFAOYSA-N`
Compound Name	N-(1-azabicyclo[2.2.2]octan-3-yl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide
Canonical SMILES	`Cc1nc(Nc2ncc(C(=O)NC3CN4CCC3CC4)s2)cc(N2CCN(CCO)CC2)n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.65
Source	BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P12931	SRC	Homo sapiens	Human	PF07714 PF00017 PF00018	7.1	IC50	BindingDB
P00519	ABL1	Homo sapiens	Human	PF08919 PF07714 PF00017 PF00018	6.4	IC50	BindingDB
P14867	GABRA1	Homo sapiens	Human	PF02931 PF02932	6.4	IC50	BindingDB