2-[4-[4-[[7-(2-Cyanophenyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]-3-methoxyphenyl]piperidin-1-yl]acetamide

InChIKey	`MOWRRSWYFUOCAR-UHFFFAOYSA-N`
Compound Name	2-[4-[4-[[7-(2-Cyanophenyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]-3-methoxyphenyl]piperidin-1-yl]acetamide
Canonical SMILES	`COc1cc(C2CCN(CC(N)=O)CC2)ccc1Nc1ncc2ccc(-c3ccccc3C#N)n2n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.63
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9UM73	ALK	Homo sapiens	Human	PF12810 PF00629 PF07714	7.2	IC50	ChEMBL;BindingDB
P06748	NPM1	Homo sapiens	Human	PF16276 PF03066	6.6	IC50	ChEMBL
P06213	INSR	Homo sapiens	Human	PF00757 PF17870 PF07714 PF01030	6.1	IC50	ChEMBL;BindingDB