N-(2,6-Difluorophenyl)-5-(3-(2-(5-ethyl-4-(4-(4-(methanesulfonyl)piperazin-1-yl)piperidin-1-yl)-2-methoxyanilino)pyrimidin-4-yl)imidazo(1,2-a)pyridin-2-yl)-2-methoxybenzamide

InChIKey	`MOSKATHMXWSZTQ-UHFFFAOYSA-N`
Compound Name	N-(2,6-Difluorophenyl)-5-(3-(2-(5-ethyl-4-(4-(4-(methanesulfonyl)piperazin-1-yl)piperidin-1-yl)-2-methoxyanilino)pyrimidin-4-yl)imidazo(1,2-a)pyridin-2-yl)-2-methoxybenzamide
Canonical SMILES	`CCc1cc(Nc2nccc(-c3c(-c4ccc(OC)c(C(=O)Nc5c(F)cccc5F)c4)nc4ccccn34)n2)c(OC)cc1N1CCC(N2CCN(S(C)(=O)=O)CC2)CC1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	16
Pfam Stratification	Cross-Family
Avg pChEMBL	7.11
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O75716	STK16	Homo sapiens	Human	PF00069	8.8	pIC50	TTD_MultiTarget
P06729	CD2	Homo sapiens	Human	PF05790 PF07686	8.8	pIC50	TTD_MultiTarget
P16591	FER	Homo sapiens	Human	PF00611 PF07714 PF00017	7.9	IC50	ChEMBL
P42685	FRK	Homo sapiens	Human	PF07714 PF00017 PF00018	7.8	IC50	ChEMBL
P06213	INSR	Homo sapiens	Human	PF00757 PF17870 PF07714 PF01030	7.4	IC50	ChEMBL;BindingDB
P08069	IGF1R	Homo sapiens	Human	PF00757 PF07714 PF01030	7.2	IC50	ChEMBL;BindingDB
O75914	PAK3	Homo sapiens	Human	PF00786 PF00069	7.0	IC50	ChEMBL
P07332	FES	Homo sapiens	Human	PF00611 PF07714 PF00017	6.8	IC50	ChEMBL
O14965	AURKA	Homo sapiens	Human	PF00069	6.8	IC50	ChEMBL
P35916	FLT4	Homo sapiens	Human	PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854	6.8	IC50	ChEMBL
P08631	HCK	Homo sapiens	Human	PF07714 PF00017 PF00018	6.6	IC50	ChEMBL
Q06187	BTK	Homo sapiens	Human	PF00779 PF00169 PF07714 PF00017 PF00018	6.5	IC50	ChEMBL
Q13882	PTK6	Homo sapiens	Human	PF07714 PF00017 PF00018	6.5	IC50	ChEMBL
Q05397	PTK2	Homo sapiens	Human	PF21477 PF00373 PF18038 PF03623 PF07714	6.4	IC50	ChEMBL
P14616	INSRR	Homo sapiens	Human	PF00041 PF00757 PF07714 PF01030	6.3	IC50	ChEMBL
P04629	NTRK1	Homo sapiens	Human	PF13855 PF16920 PF07714 PF18613	6.2	IC50	ChEMBL