Molecule Details
InChIKeyMOHYPRXHKRXDSE-UHFFFAOYSA-N
Compound Name4-(4-Fluorophenyl)-3-pyridin-4-yl-1-(2,4,6-trichlorophenyl)pyrazol-5-amine
Canonical SMILESNc1c(-c2ccc(F)cc2)c(-c2ccncc2)nn1-c1c(Cl)cc(Cl)cc1Cl
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL7.04
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
Q07912 TNK2 Homo sapiens Human PF09027 PF11555 PF07714 PF22931 PF14604 7.5 IC50 ChEMBL;BindingDB
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 7.5 IC50 ChEMBL;BindingDB
O43353 RIPK2 Homo sapiens Human PF00619 PF07714 7.4 IC50 ChEMBL;BindingDB
Q13882 PTK6 Homo sapiens Human PF07714 PF00017 PF00018 7.2 IC50 ChEMBL;BindingDB
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 7.0 IC50 ChEMBL;BindingDB
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 7.0 IC50 ChEMBL;BindingDB
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 6.4 IC50 ChEMBL;BindingDB
P15056 BRAF Homo sapiens Human PF00130 PF07714 PF02196 6.4 IC50 ChEMBL;BindingDB