8-[5-(1-methylindazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1,3,8-triazaspiro[4.5]decane-2,4-dione

InChIKey	`MOFLRZQOEVPOMU-UHFFFAOYSA-N`
Compound Name	8-[5-(1-methylindazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Canonical SMILES	`Cn1ncc2cc(-c3cnc4[nH]ccc4c3N3CCC4(CC3)NC(=O)NC4=O)ccc21`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.58
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9BWU1	CDK19	Homo sapiens	Human	PF00069	8.7	IC50	ChEMBL;BindingDB
P24863	CCNC	Homo sapiens	Human	PF16899 PF00134	8.5	IC50	ChEMBL;BindingDB
P49336	CDK8	Homo sapiens	Human	PF00069	8.5	IC50	ChEMBL