Molecule Details
InChIKeyMMMPFWNSQKXKDX-UHFFFAOYSA-N
Compound Name3-[(5-methylsulfanyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]propan-1-ol
Canonical SMILESCSc1c[nH]c2ncnc(NCCCO)c12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)14
Pfam Stratification Cross-Family
Avg pChEMBL6.33
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (14)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.4 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.7 Ki ChEMBL
O15075 DCLK1 Homo sapiens Human PF03607 PF00069 6.5 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.5 Ki ChEMBL
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.4 Ki ChEMBL
Q13188 STK3 Homo sapiens Human PF11629 PF00069 6.2 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.2 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.1 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.0 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.0 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.0 Ki ChEMBL