Molecule Details
InChIKeyMMJJNHOIVCGAAP-UHFFFAOYSA-N
Canonical SMILESCCOC(=O)N1CCC(CN(Cc2ccc(Cl)cc2)Cc2ccc([N+](=O)[O-])s2)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL6.13
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB14013
Drug NameSR-9009
CAS Number1379686-30-2
Groups experimental
ATC Codes nan
DescriptionSR-9009 is a REV-ERB agonist. SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues [A32628].

Categories: Sulfur Compounds
Cross-references: BindingDB: 50366238 CHEMBL1961796 ChemSpider: 28487410 Wikipedia: SR9009
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P20393 NR1D1 Homo sapiens Human PF00104 PF00105 6.2 IC50 ChEMBL;BindingDB
Q14995 NR1D2 Homo sapiens Human PF00104 PF00105 6.1 IC50 ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P20393 NR1D1 Nuclear receptor subfamily 1 group D member 1 agonist targets
Q14995 NR1D2 Nuclear receptor subfamily 1 group D member 2 agonist targets