Molecule Details
InChIKeyMMFBBQQGBVPLQQ-UHFFFAOYSA-N
Compound Name6-[(2-Aminocyclohexyl)amino]-2-(3-chloroanilino)pyridine-3-carboxamide
Canonical SMILESNC(=O)c1ccc(NC2CCCCC2N)nc1Nc1cccc(Cl)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)13
Pfam Stratification Cross-Family
Avg pChEMBL6.46
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (13)
Target Gene Organism Category Pfam pChEMBL Type Source
P36888 FLT3 Homo sapiens Human PF00047 PF07714 7.0 Ki ChEMBL
Q5S007 LRRK2 Homo sapiens Human PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 7.0 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.6 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.6 Ki ChEMBL
Q9H0K1 SIK2 Homo sapiens Human PF00069 PF23312 6.6 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.5 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.5 Ki ChEMBL
Q06418 TYRO3 Homo sapiens Human PF00041 PF07679 PF07714 6.4 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 6.4 Ki ChEMBL
P29376 LTK Homo sapiens Human PF12810 PF07714 6.3 Ki ChEMBL
Q13188 STK3 Homo sapiens Human PF11629 PF00069 6.1 Ki ChEMBL
P53779 MAPK10 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q02750 MAP2K1 Homo sapiens Human PF00069 6.0 Ki ChEMBL