8-hydroxy-N-[5-[[2-(1-methylpyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-1-oxo-2-azaspiro[4.4]nonane-2-carboxamide

InChIKey	`MLFZJIDNGFABRH-UHFFFAOYSA-N`
Compound Name	8-hydroxy-N-[5-[[2-(1-methylpyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-1-oxo-2-azaspiro[4.4]nonane-2-carboxamide
Canonical SMILES	`Cn1cc(-c2cc(Oc3ccc(NC(=O)N4CCC5(CCC(O)C5)C4=O)nc3)ccn2)cn1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.68
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P07333	CSF1R	Homo sapiens	Human	PF00047 PF25305 PF07714	8.2	IC50	ChEMBL;BindingDB
P10721	KIT	Homo sapiens	Human	PF00047 PF07714	7.6	IC50	ChEMBL;BindingDB
P16234	PDGFRA	Homo sapiens	Human	PF07679 PF25305 PF07714	7.2	IC50	ChEMBL;BindingDB