Ethyl 3-oxo-3-[[3-[5-(3-phenoxyprop-1-ynyl)thiophen-3-yl]-1,4-dihydroindeno[2,1-d]pyrazol-5-yl]amino]propanoate

InChIKey	`MKTIGUPWZDQDGK-UHFFFAOYSA-N`
Compound Name	Ethyl 3-oxo-3-[[3-[5-(3-phenoxyprop-1-ynyl)thiophen-3-yl]-1,4-dihydroindeno[2,1-d]pyrazol-5-yl]amino]propanoate
Canonical SMILES	`CCOC(=O)CC(=O)Nc1cccc2c1Cc1c-2n[nH]c1-c1csc(C#CCOc2ccccc2)c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	6.5
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P17948	FLT1	Homo sapiens	Human	PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854	6.8	IC50	ChEMBL;BindingDB
P35968	KDR	Homo sapiens	Human	PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854	6.6	IC50	ChEMBL;BindingDB
Q02161	RHD	Homo sapiens	Human	PF00909	6.4	pIC50	TTD_MultiTarget
P10721	KIT	Homo sapiens	Human	PF00047 PF07714	6.2	IC50	ChEMBL;BindingDB