Molecule Details
InChIKeyMKLKAQMPKHNQPR-NSHDSACASA-N
Compound NamePalupiprant
Canonical SMILESC[C@H](NC(=O)c1c(C(F)F)nn(C)c1Oc1cccc(C(F)(F)F)c1)c1ccc(C(=O)O)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.06
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB21421
Drug NamePalupiprant
CAS Number1369489-71-3
Groups investigational
ATC Codes nan
DescriptionPalupiprant is a small molecule drug. Palupiprant has a monoisotopic molecular weight of 483.12 Da.
Categories: Acids, Carbocyclic Benzene Derivatives
Cross-references: BindingDB: 119448 CHEMBL3670685 ZINC: ZINC000114766778
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P35408 PTGER4 Homo sapiens Human PF00001 8.1 IC50 ChEMBL;BindingDB
P43116 PTGER2 Homo sapiens Human PF00001 6.0 IC50 ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P35408 PTGER4 Prostaglandin E2 receptor EP4 subtype antagonist targets