(3-{3-[4-(2-Methoxy-phenyl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-pyrrolo[2,3-b]pyridin-1-yl}-propyl)-carbamic acid tert-butyl ester

InChIKey	`MJSXSLBYCSPRHR-UHFFFAOYSA-N`
Compound Name	(3-{3-[4-(2-Methoxy-phenyl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-pyrrolo[2,3-b]pyridin-1-yl}-propyl)-carbamic acid tert-butyl ester
Canonical SMILES	`COc1ccccc1C1=C(c2cn(CCCNC(=O)OC(C)(C)C)c3ncccc23)C(=O)NC1=O`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	10
Pfam Stratification	Cross-Family
Avg pChEMBL	6.96
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P49841	GSK3B	Homo sapiens	Human	PF00069	8.2	IC50	ChEMBL;BindingDB
P06493	CDK1	Homo sapiens	Human	PF00069	7.2	pIC50	TTD_MultiTarget
P20248	CCNA2	Homo sapiens	Human	PF02984 PF00134 PF16500	7.2	IC50	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	7.2	pIC50	TTD_MultiTarget
P78396	CCNA1	Homo sapiens	Human	PF02984 PF00134 PF16500	7.2	IC50	ChEMBL
O95067	CCNB2	Homo sapiens	Human	PF02984 PF00134	6.8	IC50	ChEMBL
P14635	CCNB1	Homo sapiens	Human	PF02984 PF00134	6.8	IC50	ChEMBL
Q8WWL7	CCNB3	Homo sapiens	Human	PF02984 PF00134	6.8	IC50	ChEMBL
O15530	PDPK1	Homo sapiens	Human	PF14593 PF00069	6.2	IC50	ChEMBL;BindingDB
P51812	RPS6KA3	Homo sapiens	Human	PF00069 PF00433	6.2	IC50	ChEMBL;BindingDB