Molecule Details
InChIKeyMJOCJDMQRCJQJF-UHFFFAOYSA-N
Compound Name3-(6-Ethoxynaphthalen-2-Yl)-1-(Propan-2-Yl)-1h-Pyrazolo[3,4-D]pyrimidin-4-Amine
Canonical SMILESCCOc1ccc2cc(-c3nn(C(C)C)c4ncnc(N)c34)ccc2c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL7.33
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 7.3 IC50 ChEMBL;BindingDB
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 6.7 IC50 ChEMBL;BindingDB
P08631 HCK Homo sapiens Human PF07714 PF00017 PF00018 6.7 IC50 ChEMBL;BindingDB
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 6.2 IC50 ChEMBL;BindingDB
Q8MMZ7 PKG Toxoplasma gondii Pathogen PF00027 PF00069 8.3 IC50 BindingDB
Q9BJF5 CDPK1 Toxoplasma gondii Pathogen PF13499 PF00069 8.3 IC50 ChEMBL;BindingDB
A3FQ16 Cryptosporidium parvum (strain Iowa II) Pathogen PF13499 PF00069 7.9 IC50 BindingDB