Molecule Details
| InChIKey | MJIVRKPEXXHNJT-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2,4-Pyridinedicarboxylic acid |
| Canonical SMILES | O=C(O)c1ccnc(C(=O)O)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 9 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.47 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (9)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q12797 | ASPH | Homo sapiens | Human | PF05279 PF05118 PF13432 | 7.6 | IC50 | ChEMBL;BindingDB |
| Q9H3R0 | KDM4C | Homo sapiens | Human | PF02373 PF02375 PF13831 PF18104 PF13832 | 6.7 | IC50 | ChEMBL;BindingDB |
| B2RXH2 | KDM4E | Homo sapiens | Human | PF02373 PF02375 | 6.5 | IC50 | ChEMBL |
| Q9GZT9 | EGLN1 | Homo sapiens | Human | PF13640 PF01753 | 6.4 | Kd | ChEMBL;BindingDB |
| P41229 | KDM5C | Homo sapiens | Human | PF01388 PF02373 PF02375 PF21323 PF00628 PF08429 PF02928 | 6.3 | IC50 | ChEMBL;BindingDB |
| Q8N371 | KDM8 | Homo sapiens | Human | PF24472 PF13621 | 6.3 | IC50 | ChEMBL |
| O75164 | KDM4A | Homo sapiens | Human | PF02373 PF02375 PF13831 PF18104 PF13832 | 6.2 | IC50 | ChEMBL |
| P29375 | KDM5A | Homo sapiens | Human | PF01388 PF02373 PF02375 PF21323 PF00628 PF08429 PF02928 | 6.1 | IC50 | ChEMBL;BindingDB |
| O43151 | TET3 | Homo sapiens | Human | PF12851 PF02008 | 6.1 | IC50 | ChEMBL |