3-benzyl-5-(1H-indazol-5-yl)-N,N-dimethyltriazole-4-carboxamide

InChIKey	`MIYRKQLKDQNUKZ-UHFFFAOYSA-N`
Compound Name	3-benzyl-5-(1H-indazol-5-yl)-N,N-dimethyltriazole-4-carboxamide
Canonical SMILES	`CN(C)C(=O)c1c(-c2ccc3[nH]ncc3c2)nnn1Cc1ccccc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	23
Pfam Stratification	Cross-Family
Avg pChEMBL	6.47
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P51817	PRKX	Homo sapiens	Human	PF00069	8.0	Ki	ChEMBL
O75116	ROCK2	Homo sapiens	Human	PF25346 PF00069 PF08912	7.4	Ki	ChEMBL
O14965	AURKA	Homo sapiens	Human	PF00069	6.8	Ki	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	6.7	Ki	ChEMBL
P49841	GSK3B	Homo sapiens	Human	PF00069	6.7	Ki	ChEMBL
Q13464	ROCK1	Homo sapiens	Human	PF25346 PF00069 PF08912	6.7	Ki	ChEMBL
Q5VT25	CDC42BPA	Homo sapiens	Human	PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433	6.7	Ki	ChEMBL
P23443	RPS6KB1	Homo sapiens	Human	PF00069 PF00433	6.6	Ki	ChEMBL
P17612	PRKACA	Homo sapiens	Human	PF00069	6.5	Ki	ChEMBL
P49840	GSK3A	Homo sapiens	Human	PF00069	6.5	Ki	ChEMBL
P28482	MAPK1	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
Q13976	PRKG1	Homo sapiens	Human	PF00027 PF16808 PF00069	6.3	Ki	ChEMBL
Q96GD4	AURKB	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
Q9HAZ1	CLK4	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
P06493	CDK1	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL
Q12851	MAP4K2	Homo sapiens	Human	PF00780 PF00069	6.2	Ki	ChEMBL
Q13131	PRKAA1	Homo sapiens	Human	PF16579 PF21147 PF00069	6.2	Ki	ChEMBL
Q13237	PRKG2	Homo sapiens	Human	PF00027 PF00069	6.2	Ki	ChEMBL
O00311	CDC7	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL;BindingDB
Q16513	PKN2	Homo sapiens	Human	PF02185 PF00069 PF00433	6.1	Ki	ChEMBL
O00444	PLK4	Homo sapiens	Human	PF00069 PF18190 PF18409	6.0	Ki	ChEMBL
P27448	MARK3	Homo sapiens	Human	PF02149 PF00069 PF00627	6.0	Ki	ChEMBL
P52333	JAK3	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	6.0	Ki	ChEMBL