Molecule Details
| InChIKey | MINIPTTTZPEEKT-DHIUTWEWSA-N |
|---|---|
| Compound Name | Pde1-IN-4 |
| Canonical SMILES | CC1=C(C(=O)O[C@H](C)c2ccccc2)C(c2ccc3c(cnn3C)c2)C(C(=O)O[C@H](C)c2ccccc2)=C(C)N1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.7 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q14123 | PDE1C | Homo sapiens | Human | PF00233 PF08499 | 8.0 | IC50 | ChEMBL |
| P54750 | PDE1A | Homo sapiens | Human | PF00233 PF08499 | 6.8 | IC50 | ChEMBL |
| Q01064 | PDE1B | Homo sapiens | Human | PF00233 PF08499 | 6.5 | IC50 | ChEMBL |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 6.2 | IC50 | ChEMBL |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 6.0 | IC50 | ChEMBL |