Molecule Details
InChIKeyMIMOHMCANSGXIG-MRXNPFEDSA-N
Compound NamePkmyt1-IN-3
Canonical SMILESCc1ccc(O)c(C)c1-c1cc(-c2cc(F)nc(N3CC[C@@H](N)C3)c2)cc(C(N)=O)c1N
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)15
Pfam Stratification Cross-Family
Avg pChEMBL7.55
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (15)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13882 PTK6 Homo sapiens Human PF07714 PF00017 PF00018 8.1 IC50 ChEMBL
P09769 FGR Homo sapiens Human PF07714 PF00017 PF00018 8.0 IC50 ChEMBL
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 8.0 IC50 ChEMBL
Q08345 DDR1 Homo sapiens Human PF21114 PF00754 PF07714 8.0 IC50 ChEMBL
P42684 ABL2 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 8.0 IC50 ChEMBL
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 7.8 IC50 ChEMBL
Q99640 PKMYT1 Homo sapiens Human PF00069 7.8 IC50 ChEMBL
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 7.7 IC50 ChEMBL
P29323 EPHB2 Homo sapiens Human PF14575 PF25599 PF01404 PF07699 PF00041 PF07714 PF00536 7.6 IC50 ChEMBL
P54762 EPHB1 Homo sapiens Human PF14575 PF25599 PF01404 PF00041 PF07714 PF00536 7.4 IC50 ChEMBL
P08631 HCK Homo sapiens Human PF07714 PF00017 PF00018 7.3 IC50 ChEMBL
P51451 BLK Homo sapiens Human PF07714 PF00017 PF00018 7.2 IC50 ChEMBL
P21709 EPHA1 Homo sapiens Human PF14575 PF25599 PF01404 PF07699 PF00041 PF07714 PF00536 7.0 IC50 ChEMBL
P54760 EPHB4 Homo sapiens Human PF14575 PF25599 PF01404 PF07699 PF00041 PF07714 PF00536 6.9 IC50 ChEMBL
Q07912 TNK2 Homo sapiens Human PF09027 PF11555 PF07714 PF22931 PF14604 6.6 IC50 ChEMBL