4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-[4-(4-isopropyl-phenylethynyl)-phenylsulfanyl]-butyric acid

InChIKey	`MIBJKVVEWJVVMR-UHFFFAOYSA-N`
Compound Name	4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-[4-(4-isopropyl-phenylethynyl)-phenylsulfanyl]-butyric acid
Canonical SMILES	`CC(C)c1ccc(C#Cc2ccc(SC(CCN3C(=O)c4ccccc4C3=O)C(=O)O)cc2)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.53
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P08253	MMP2	Homo sapiens	Human	PF00040 PF00045 PF00413	8.8	pIC50	TTD_MultiTarget
P14780	MMP9	Homo sapiens	Human	PF00040 PF00045 PF00413	8.3	IC50	ChEMBL;BindingDB