Molecule Details
InChIKeyMGNQNQOSSLCUFP-UHFFFAOYSA-N
Compound Namep38 MAP Kinase-IN-1
Canonical SMILESFc1ccc(-c2nc3occn3c2-c2ccnc(NC3CCNCC3)n2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Cross-Family
Avg pChEMBL6.53
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
P45984 MAPK9 Homo sapiens Human PF00069 7.2 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 7.1 Ki ChEMBL
P48729 CSNK1A1 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.8 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.7 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q9Y6M4 CSNK1G3 Homo sapiens Human PF12605 PF00069 6.6 Ki ChEMBL
Q9UM73 ALK Homo sapiens Human PF12810 PF00629 PF07714 6.3 Ki ChEMBL
Q9HCP0 CSNK1G1 Homo sapiens Human PF12605 PF00069 6.1 Ki ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 6.0 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9P1W9 PIM2 Homo sapiens Human PF00069 6.0 Ki ChEMBL