Molecule Details
| InChIKey | MGARWHQGMCYTAL-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-{6-[(3-Chlorobenzyl)oxy]naphthalen-2-Yl}-1-(Propan-2-Yl)-1h-Pyrazolo[3,4-D]pyrimidin-4-Amine |
| Canonical SMILES | CC(C)n1nc(-c2ccc3cc(OCc4cccc(Cl)c4)ccc3c2)c2c(N)ncnc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.41 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P12931 | SRC | Homo sapiens | Human | PF07714 PF00017 PF00018 | 6.5 | IC50 | ChEMBL;BindingDB |
| Q8MMZ7 | PKG | Toxoplasma gondii | Pathogen | PF00027 PF00069 | 8.3 | IC50 | BindingDB |
| Q9BJF5 | CDPK1 | Toxoplasma gondii | Pathogen | PF13499 PF00069 | 8.3 | IC50 | ChEMBL;BindingDB |
| A3FQ16 | Cryptosporidium parvum (strain Iowa II) | Pathogen | PF13499 PF00069 | 6.6 | IC50 | BindingDB |