InChIKey	METQSPRSQINEEU-HXCATZOESA-N
Compound Name	Drospirenone
Canonical SMILES	C[C@]12CCC(=O)C=C1[C@@H]1C[C@@H]1[C@H]1[C@@H]3[C@@H]4C[C@@H]4[C@@]4(CCC(=O)O4)[C@@]3(C)CC[C@@H]12
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.35
Source	BindingDB;ChEMBL

DrugBank ID	DB01395
Drug Name	Drospirenone
CAS Number	67392-87-4
Groups	approved investigational
ATC Codes	G03AA18 G03AC10 G03FA17 G03AA12
Description	Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with [Ethinyl estradiol].[L7973] Most recently, it was approved by both Health Canada and the FDA in combination with [Estetrol] as an oral contraceptive therapy.[L33199,L33174] Aside from its ...

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Categories: Adrenal Cortex Hormones Agents causing hyperkalemia Androstanes Combination Contraceptives (with Estrogen and derivatives) Contraceptive Agents, Female Contraceptives, Oral Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A4 Substrates (strength unknown) Cytochrome P-450 Substrates Diuretics Fused-Ring Compounds Genito Urinary System and Sex Hormones Hormonal Contraceptives for Systemic Use Hormone Antagonists Hormones, Hormone Substitutes, and Hormone Antagonists Hyperglycemia-Associated Agents Mineralocorticoid Receptor Antagonists Natriuretic Agents Progesterone Congeners Progestin Contraceptives Progestins Sex Hormones and Modulators of the Genital System Steroids

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Cross-references: BindingDB: 150275 ChEBI: 50838 CHEMBL1509 ChemSpider: 62105 Drugs Product Database (DPD): 13375 D03917 PharmGKB: PA164749409 PubChem:68873 PubChem:46507653 RxCUI: 11636 Therapeutic Targets Database: DAP001206 Wikipedia: Drospirenone ZINC: ZINC000003927200