InChIKey	METKIMKYRPQLGS-UHFFFAOYSA-N
Compound Name	Atenolol
Canonical SMILES	CC(C)NCC(O)COc1ccc(CC(N)=O)cc1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	5
Pfam Stratification	Homologous
Avg pChEMBL	6.64
Source	ChEMBL;BindingDB

DrugBank ID	DB00335
Drug Name	Atenolol
CAS Number	29122-68-7
Groups	approved investigational
ATC Codes	C07CB53 C07AB03 C07FB03 C07DB01 C07BB03 C07CB03
Description	Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize.[A178429] Beta-blockers quickly became popular...

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Categories: Adrenergic Agents Adrenergic Antagonists Adrenergic beta-1 Receptor Antagonists Adrenergic beta-Antagonists Agents causing hyperkalemia Alcohols Amines Amino Alcohols Antiarrhythmic agents Antihypertensive Agents Antihypertensive Agents Indicated for Hypertension Autonomic Agents BSEP/ABCB11 Substrates Beta Blocking Agents and Thiazides Beta Blocking Agents, Selective Beta Blocking Agents, Selective, and Thiazides Beta blocking agents and calcium channel blockers Beta-Blockers (Beta1 Selective) Bradycardia-Causing Agents Cardiovascular Agents Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 Substrates Hypotensive Agents Peripheral Nervous System Agents QTc shortening agents Sympatholytics

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Cross-references: BindingDB: 25753 ChEBI: 2904 CHEMBL24 ChemSpider: 2162 Drugs Product Database (DPD): 2041 Guide to Pharmacology: 548 IUPHAR: 548 D00235 PharmGKB: PA448499 PubChem:2249 PubChem:46506915 RxCUI: 1202 Therapeutic Targets Database: DAP000482 Wikipedia: Atenolol