Molecule Details
InChIKeyMEKSQRMXWZHFIP-UHFFFAOYSA-N
Compound NameCumi-101
Canonical SMILESCOc1ccccc1N1CCN(CCCCn2ncc(=O)n(C)c2=O)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)13
Pfam Stratification Cross-Family
Avg pChEMBL7.61
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (13)
Target Gene Organism Category Pfam pChEMBL Type Source
P08908 HTR1A Homo sapiens Human PF00001 9.8 Ki ChEMBL;BindingDB
P25100 ADRA1D Homo sapiens Human PF00001 8.2 Ki ChEMBL
P35348 ADRA1A Homo sapiens Human PF00001 8.2 Ki ChEMBL
P35368 ADRA1B Homo sapiens Human PF00001 8.2 Ki ChEMBL
P34969 HTR7 Homo sapiens Human PF00001 7.9 Ki ChEMBL
P18825 ADRA2C Homo sapiens Human PF00001 7.8 Ki ChEMBL
P21917 DRD4 Homo sapiens Human PF00001 7.7 Ki ChEMBL
Q99720 SIGMAR1 Homo sapiens Human PF04622 7.2 Ki ChEMBL;BindingDB
P41595 HTR2B Homo sapiens Human PF00001 7.1 Ki ChEMBL
P28221 HTR1D Homo sapiens Human PF00001 7.0 Ki ChEMBL
P08913 ADRA2A Homo sapiens Human PF00001 7.0 Ki ChEMBL
P18089 ADRA2B Homo sapiens Human PF00001 6.6 Ki ChEMBL
P28222 HTR1B Homo sapiens Human PF00001 6.2 Ki ChEMBL