Molecule Details
| InChIKey | MEELSFYQUGSNNK-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-[3-[(1-Benzylpiperidin-4-yl)methyl]-2-oxo-5-phenylmethoxy-1,3-diazinan-1-yl]benzenecarboximidamide |
| Canonical SMILES | N=C(N)c1cccc(N2CC(OCc3ccccc3)CN(CC3CCN(Cc4ccccc4)CC3)C2=O)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.19 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P07477 | PRSS1 | Homo sapiens | Human | PF00089 | 6.3 | Ki | ChEMBL;BindingDB |
| P07478 | PRSS2 | Homo sapiens | Human | PF00089 | 6.3 | Ki | ChEMBL |
| P35030 | PRSS3 | Homo sapiens | Human | PF00089 | 6.3 | Ki | ChEMBL |
| P05981 | HPN | Homo sapiens | Human | PF09272 PF00089 | 6.1 | Ki | ChEMBL;BindingDB |
| P00742 | F10 | Homo sapiens | Human | PF00008 PF14670 PF00594 PF00089 | 6.0 | Ki | ChEMBL;BindingDB |