Molecule Details
InChIKeyMCUJKPPARUPFJM-UWCCDQBKSA-N
Compound NameAzd-1208
Canonical SMILESN[C@@H]1CCCN(c2c(/C=C3\SC(=O)NC3=O)cccc2-c2ccccc2)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)11
Pfam Stratification Cross-Family
Avg pChEMBL7.74
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
Q96AD5 PNPLA2 Homo sapiens Human PF01734 10.8 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 9.4 IC50 ChEMBL
Q86V86 PIM3 Homo sapiens Human PF00069 8.7 IC50 ChEMBL
Q8TD08 MAPK15 Homo sapiens Human PF00069 8.3 Kd ChEMBL
Q9P1W9 PIM2 Homo sapiens Human PF00069 8.3 IC50 ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 7.4 Kd ChEMBL
P10415 BCL2 Homo sapiens Human PF00452 PF02180 7.1 Ki ChEMBL
Q16566 CAMK4 Homo sapiens Human PF00069 6.4 Kd ChEMBL
P53355 DAPK1 Homo sapiens Human PF00023 PF12796 PF13637 PF00531 PF00069 6.4 Kd ChEMBL
Q9H422 HIPK3 Homo sapiens Human PF00069 6.3 Kd ChEMBL
O94768 STK17B Homo sapiens Human PF00069 6.0 Kd ChEMBL