Molecule Details
InChIKeyMCKPYPWHBUXLEZ-UHFFFAOYSA-N
Compound NameThieno[2,3-c]pyridine-2-carboxamide,7-amino-4-[4-(2-benzoxazolylamino)phenyl]-
Canonical SMILESNC(=O)c1cc2c(-c3ccc(Nc4nc5ccccc5o4)cc3)cnc(N)c2s1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)21
Pfam Stratification Cross-Family
Avg pChEMBL6.63
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (21)
Target Gene Organism Category Pfam pChEMBL Type Source
P49336 CDK8 Homo sapiens Human PF00069 8.6 Ki ChEMBL
P48729 CSNK1A1 Homo sapiens Human PF00069 8.1 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.7 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 7.4 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 7.4 Ki ChEMBL
Q5S007 LRRK2 Homo sapiens Human PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 6.8 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.5 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.5 Ki ChEMBL
P29376 LTK Homo sapiens Human PF12810 PF07714 6.3 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.2 Ki ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.2 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.2 Ki ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.2 Ki ChEMBL
P07333 CSF1R Homo sapiens Human PF00047 PF25305 PF07714 6.1 Ki ChEMBL
P36507 MAP2K2 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q7L7X3 TAOK1 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q02750 MAP2K1 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.0 Ki ChEMBL