2-((2-((2-Methyl-4-(1-propyl-1,2,5,6-tetrahydropyridin-3-yl)phenyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)benzamide

InChIKey	`MCHOTIIDAJHLED-UHFFFAOYSA-N`
Compound Name	2-((2-((2-Methyl-4-(1-propyl-1,2,5,6-tetrahydropyridin-3-yl)phenyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)benzamide
Canonical SMILES	`CCCN1CCC=C(c2ccc(Nc3nc(Nc4ccccc4C(N)=O)c4cc[nH]c4n3)c(C)c2)C1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	8.34
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9UM73	ALK	Homo sapiens	Human	PF12810 PF00629 PF07714	9.0	IC50	ChEMBL
P06729	CD2	Homo sapiens	Human	PF05790 PF07686	8.3	pIC50	TTD_MultiTarget
P08069	IGF1R	Homo sapiens	Human	PF00757 PF07714 PF01030	8.3	IC50	ChEMBL;BindingDB
P06213	INSR	Homo sapiens	Human	PF00757 PF17870 PF07714 PF01030	8.2	IC50	ChEMBL
P45983	MAPK8	Homo sapiens	Human	PF00069	7.9	IC50	ChEMBL