Molecule Details
| InChIKey | MBYYLRDCKQHUGM-GOSISDBHSA-N |
|---|---|
| Compound Name | (R)-4-((4-(3-cyano-4-((1-(2-hydroxyacetyl)pyrrolidin-3-yl)oxy)phenyl)-1,3,5-triazin-2-yl)amino)benzamide |
| Canonical SMILES | N#Cc1cc(-c2ncnc(Nc3ccc(C(N)=O)cc3)n2)ccc1O[C@@H]1CCN(C(=O)CO)C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.22 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9UHD2 | TBK1 | Homo sapiens | Human | PF00069 PF18394 PF18396 | 7.9 | IC50 | BindingDB |
| Q14164 | IKBKE | Homo sapiens | Human | PF00069 PF18394 PF18396 | 7.6 | IC50 | BindingDB |
| O60674 | JAK2 | Homo sapiens | Human | PF18379 PF18377 PF17887 PF07714 PF21990 | 6.2 | IC50 | ChEMBL;BindingDB |