MBKBRIBQHFBRHO-UDKICSLYSA-N

InChIKey	`MBKBRIBQHFBRHO-UDKICSLYSA-N`
Canonical SMILES	`Cn1cc(Nc2ncc3cnn([C@@H]4C[C@H]5C[C@H]5C4)c3n2)cc1C(=O)N1CCC[C@H]1CN1CCOCC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	8.2
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O14965	AURKA	Homo sapiens	Human	PF00069	8.5	IC50	ChEMBL;BindingDB
Q96GD4	AURKB	Homo sapiens	Human	PF00069	8.4	IC50	ChEMBL;BindingDB
P06493	CDK1	Homo sapiens	Human	PF00069	7.7	IC50	ChEMBL;BindingDB