MBGUKRYARWDEQD-INIZCTEOSA-N

InChIKey	`MBGUKRYARWDEQD-INIZCTEOSA-N`
Canonical SMILES	`Cc1cccc(-c2nc(Nc3ccncc3F)c3c(CN4CC[C@H](O)C4)ccn3n2)n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Cross-Family
Avg pChEMBL	8.01
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P36897	TGFBR1	Homo sapiens	Human	PF01064 PF00069 PF08515	9.3	IC50	ChEMBL;BindingDB
P37173	TGFBR2	Homo sapiens	Human	PF08917 PF07714	6.7	IC50	ChEMBL;BindingDB