Molecule Details
| InChIKey | MAALNNWDTHSDCS-UHFFFAOYSA-N |
|---|---|
| Compound Name | Cyclobuten-1-yl-[3-[9-methyl-6-[4-(trifluoromethoxy)phenyl]purin-2-yl]azetidin-1-yl]methanone |
| Canonical SMILES | Cn1cnc2c(-c3ccc(OC(F)(F)F)cc3)nc(C3CN(C(=O)C4=CCC4)C3)nc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.32 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q15561 | TEAD4 | Homo sapiens | Human | PF01285 PF17725 | 8.7 | IC50 | ChEMBL |
| Q15562 | TEAD2 | Homo sapiens | Human | PF01285 PF17725 | 8.4 | IC50 | ChEMBL |
| P28347 | TEAD1 | Homo sapiens | Human | PF01285 PF17725 | 8.2 | IC50 | ChEMBL |
| Q99594 | TEAD3 | Homo sapiens | Human | PF01285 PF17725 | 8.1 | IC50 | ChEMBL |