Molecule Details
InChIKeyLZMOSYUFVYJEPY-UHFFFAOYSA-N
Compound NameAT-7867
Canonical SMILESClc1ccc(C2(c3ccc(-c4cn[nH]c4)cc3)CCNCC2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.53
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB07859
Drug Name4-(4-CHLOROPHENYL)-4-[4-(1H-PYRAZOL-4-YL)PHENYL]PIPERIDINE
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 16219 ChEBI: 82708 CHEMBL428462 ChemSpider: 9350229 PDB: GVP PubChem:11175137 PubChem:99444330 ZINC: ZINC000014961002
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P31751 AKT2 Homo sapiens Human PF00169 PF00069 PF00433 7.8 IC50 ChEMBL;BindingDB
P31749 AKT1 Homo sapiens Human PF00169 PF00069 PF00433 7.5 IC50 ChEMBL
Q9Y243 AKT3 Homo sapiens Human PF00169 PF00069 PF00433 7.3 IC50 ChEMBL
DrugBank Target Actions (4)
Target Gene Target Name Action Type
P17612 PRKACA cAMP-dependent protein kinase catalytic subunit alpha binder targets
P31751 AKT2 RAC-beta serine/threonine-protein kinase binder targets
P49841 GSK3B Glycogen synthase kinase-3 beta binder targets
P61925 P61925 cAMP-dependent protein kinase inhibitor alpha binder targets