Molecule Details
| InChIKey | LZJRNLRASBVRRX-ZDUSSCGKSA-N |
|---|---|
| Compound Name | (+)-Boldine |
| Canonical SMILES | COc1cc2c(cc1O)C[C@H]1c3c(cc(O)c(OC)c3-2)CCN1C |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.22 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P21728 | DRD1 | Homo sapiens | Human | PF00001 | 6.4 | IC50 | ChEMBL |
| P14416 | DRD2 | Homo sapiens | Human | PF00001 | 6.3 | IC50 | ChEMBL |
| P19784 | CSNK2A2 | Homo sapiens | Human | PF00069 | 6.2 | IC50 | ChEMBL |
| P67870 | CSNK2B | Homo sapiens | Human | PF01214 | 6.2 | IC50 | ChEMBL |
| P68400 | CSNK2A1 | Homo sapiens | Human | PF00069 | 6.2 | IC50 | ChEMBL |
| Q8NEV1 | CSNK2A3 | Homo sapiens | Human | PF00069 | 6.2 | IC50 | ChEMBL;BindingDB |