Molecule Details
| InChIKey | LZFZMUMEGBBDTC-QEJZJMRPSA-N |
|---|---|
| Compound Name | Enalaprilat |
| Canonical SMILES | C[C@H](N[C@@H](CCc1ccccc1)C(=O)O)C(=O)N1CCC[C@H]1C(=O)O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.77 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB09477 |
|---|---|
| Drug Name | Enalaprilat |
| CAS Number | 76420-72-9 |
| Groups | approved investigational |
| ATC Codes | nan |
| Description | Enalaprilat is the active metabolite of the orally available pro-drug, [enalapril]. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II. As angiotensin II is responsible for vasocon... |
Categories: Agents Acting on the Renin-Angiotensin System Agents causing angioedema Agents causing hyperkalemia Amino Acids, Peptides, and Proteins Angiotensin-Converting Enzyme Inhibitors Antihypertensive Agents Antihypertensive Agents Indicated for Hypertension Cardiovascular Agents Decreased Blood Pressure Dipeptides Drugs causing inadvertant photosensitivity Drugs that are Mainly Renally Excreted Enzyme Inhibitors Hypotensive Agents Oligopeptides Peptides Photosensitizing Agents Protease Inhibitors
Cross-references: BindingDB: 50367254 ChEBI: 4786 CHEMBL577 ChemSpider: 4575429 Drugs Product Database (DPD): 1776 C11720 D03769 PDB: EAL PubChem:5462501 PubChem:347827859 RxCUI: 3829 Wikipedia: Enalaprilat ZINC: ZINC000003812851