(1R,4R,6S,7Z,15R,17R)-17-[8-chloro-7-methoxy-2-(4-propan-2-yl-1,3-thiazol-2-yl)quinolin-4-yl]oxy-13-methyl-N-(1-methylcyclopropyl)sulfonyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.04,6]octadec-7-ene-4-carboxamide

InChIKey	`LYPMUUHUNIGEOB-OTVJIGPHSA-N`
Compound Name	(1R,4R,6S,7Z,15R,17R)-17-[8-chloro-7-methoxy-2-(4-propan-2-yl-1,3-thiazol-2-yl)quinolin-4-yl]oxy-13-methyl-N-(1-methylcyclopropyl)sulfonyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.04,6]octadec-7-ene-4-carboxamide
Canonical SMILES	`COc1ccc2c(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)NS(=O)(=O)C6(C)CC6)C[C@H]5/C=C\CCCCN(C)C(=O)[C@@H]4C3)cc(-c3nc(C(C)C)cs3)nc2c1Cl`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	9.52
Source	BindingDB;ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
A3EZI9	NS3	Hepacivirus hominis	Pathogen	PF07652 PF22027 PF02907	9.5	Ki	ChEMBL
B0B3F0	NS3/4A	Hepacivirus hominis	Pathogen	PF07652 PF01006 PF22027 PF02907	9.5	Ki	BindingDB
D2K2A8	NS4A	Hepacivirus hominis	Pathogen	PF01006	9.5	Ki	ChEMBL
K7XGM7		Hepacivirus hominis	Pathogen	PF07652 PF01006 PF22027 PF02907	9.5	Ki	BindingDB