N-[5-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinazolin-4-yl}amino)pyrimidin-2-yl]benzamide

InChIKey	`LYDTZBUSUCDSRL-UHFFFAOYSA-N`
Compound Name	N-[5-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinazolin-4-yl}amino)pyrimidin-2-yl]benzamide
Canonical SMILES	`COc1cc2c(Nc3cnc(NC(=O)c4ccccc4)nc3)ncnc2cc1OCCCN1CCOCC1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	8.68
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q96GD4	AURKB	Homo sapiens	Human	PF00069	9.0	IC50	ChEMBL;BindingDB
O14965	AURKA	Homo sapiens	Human	PF00069	8.5	IC50	ChEMBL;BindingDB
O75716	STK16	Homo sapiens	Human	PF00069	8.5	pIC50	TTD_MultiTarget