Molecule Details
InChIKeyLXIKEPCNDFVJKC-QXMHVHEDSA-N
Canonical SMILESNC(=O)N1C(=O)/C(=C(\O)c2cccs2)c2cc(Cl)ccc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)4
Pfam Stratification Cross-Family
Avg pChEMBL6.5
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB13481
Drug NameTenidap
CAS Number120210-48-2
Groups experimental
ATC Codes M01AX23
Descriptionnan

Categories: Agents causing hyperkalemia Agents that produce hypertension Alkaloids Analgesics Analgesics, Non-Narcotic Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Antiinflammatory and Antirheumatic Products Antiinflammatory and Antirheumatic Products, Non-Steroids Antirheumatic Agents Cyclooxygenase Inhibitors Enzyme Inhibitors Heterocyclic Compounds, Fused-Ring Indole Alkaloids Indoles Indolizidines Indolizines Musculo-Skeletal System Nephrotoxic agents Non COX-2 selective NSAIDS Peripheral Nervous System Agents Sensory System Agents
Cross-references: ChEBI: 35847 CHEMBL1908355 ChemSpider: 12284644 Wikipedia: Tenidap ZINC: ZINC000100001953
Target Activities (4)
Target Gene Organism Category Pfam pChEMBL Type Source
P23219 PTGS1 Homo sapiens Human PF03098 7.3 IC50 ChEMBL
P35354 PTGS2 Homo sapiens Human PF03098 6.6 IC50 ChEMBL
P11712 CYP2C9 Homo sapiens Human PF00067 6.2 IC50 ChEMBL
P05177 CYP1A2 Homo sapiens Human PF00067 6.0 IC50 ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P09917 ALOX5 Polyunsaturated fatty acid 5-lipoxygenase modulator targets