Molecule Details
| InChIKey | LXFHSCDLMBZYKY-UHFFFAOYSA-N |
|---|---|
| Compound Name | CGS 12066B-parent |
| Canonical SMILES | CN1CCN(c2nc3cc(C(F)(F)F)ccc3n3cccc23)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.37 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P28222 | HTR1B | Homo sapiens | Human | PF00001 | 8.7 | Ki | BindingDB |
| P28221 | HTR1D | Homo sapiens | Human | PF00001 | 8.6 | Ki | ChEMBL;BindingDB |
| P08908 | HTR1A | Homo sapiens | Human | PF00001 | 7.3 | IC50 | ChEMBL;BindingDB |
| P35462 | DRD3 | Homo sapiens | Human | PF00001 | 6.2 | Ki | BindingDB |
| P41595 | HTR2B | Homo sapiens | Human | PF00001 | 6.1 | Ki | BindingDB |