Molecule Details
| InChIKey | LWUDDYHYYNNIQI-UHFFFAOYSA-N |
|---|---|
| Compound Name | Tert-butyl 14-bromo-12-oxo-2,4,11-triazatetracyclo[11.4.0.02,6.07,11]heptadeca-1(17),3,5,13,15-pentaene-5-carboxylate |
| Canonical SMILES | CC(C)(C)OC(=O)c1ncn2c1C1CCCN1C(=O)c1c(Br)cccc1-2 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.43 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P14867 | GABRA1 | Homo sapiens | Human | PF02931 PF02932 | 9.1 | Ki | BindingDB |
| P47869 | GABRA2 | Homo sapiens | Human | PF02931 PF02932 | 8.9 | Ki | BindingDB |
| P34903 | GABRA3 | Homo sapiens | Human | PF02931 PF02932 | 8.9 | Ki | BindingDB |
| P31644 | GABRA5 | Homo sapiens | Human | PF02931 PF02932 | 8.6 | Ki | BindingDB |
| Q16445 | GABRA6 | Homo sapiens | Human | PF02931 PF02932 | 7.6 | Ki | BindingDB |
| P48169 | GABRA4 | Homo sapiens | Human | PF02931 PF02932 | 7.4 | Ki | BindingDB |