Molecule Details
| InChIKey | LWJGMYMNSNVCEM-UHFFFAOYSA-N |
|---|---|
| Compound Name | Pf-04418948 |
| Canonical SMILES | COc1ccc2cc(OCC3(C(=O)O)CN(C(=O)c4ccc(F)cc4)C3)ccc2c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.29 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB12024 |
|---|---|
| Drug Name | PF-04418948 |
| CAS Number | 1078166-57-0 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Pf 04418948 is under investigation in clinical trial NCT01002963 (A Study To Investigate The Safety And Toleration Of A Single Dose Of PF-04418948 In Healthy Volunteers). |
Categories: Azetines Receptors, Prostaglandin E, EP2 Subtype
Cross-references: CHEMBL3286797 ChemSpider: 29341625 PubChem:25114442 PubChem:347828339 ZINC: ZINC000095644391
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P43116 | PTGER2 | Prostaglandin E2 receptor EP2 subtype | antagonist | targets |