Molecule Details
| InChIKey | LVGFRMIIXODOEQ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 6-Hydroxy-2-(4-methoxyphenyl)-3-(1-(4-(naphthalen-1-ylamino)-4-oxobutyl)-1H-1,2,3-triazol-4-yl)benzofuran-5-carboxylic Acid |
| Canonical SMILES | COc1ccc(-c2oc3cc(O)c(C(=O)O)cc3c2-c2cn(CCCC(=O)Nc3cccc4ccccc34)nn2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.51 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P18031 | PTPN1 | Homo sapiens | Human | PF00102 | 6.7 | IC50 | ChEMBL;BindingDB |
| P29350 | PTPN6 | Homo sapiens | Human | PF00017 PF00102 | 6.5 | IC50 | ChEMBL;BindingDB |
| Q9Y2R2 | PTPN22 | Homo sapiens | Human | PF00102 | 6.5 | IC50 | ChEMBL;BindingDB |
| P08575 | PTPRC | Homo sapiens | Human | PF12567 PF00041 PF12453 PF00102 | 6.4 | IC50 | ChEMBL;BindingDB |