Molecule Details
| InChIKey | LVCMBVIHFUNWCJ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-[4-[[4-Chloro-3-(trifluoromethyl)phenyl]carbamoylamino]thiophen-2-yl]indole-1-carboxamide |
| Canonical SMILES | NC(=O)n1c(-c2cc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cs2)cc2ccccc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.84 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P35968 | KDR | Homo sapiens | Human | PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 | 6.9 | IC50 | ChEMBL;BindingDB |
| P01127 | PDGFB | Homo sapiens | Human | PF00341 PF04692 | 6.8 | IC50 | BindingDB |
| P09619 | PDGFRB | Homo sapiens | Human | PF00047 PF13927 PF25305 PF07714 | 6.8 | IC50 | ChEMBL |