Molecule Details
InChIKeyLSFLAQVDISHMNB-UHFFFAOYSA-N
Compound NameNvp-adw742
Canonical SMILESNc1ncnc2c1c(-c1cccc(OCc3ccccc3)c1)cn2C1CC(CN2CCCC2)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)13
Pfam Stratification Cross-Family
Avg pChEMBL6.51
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (13)
Target Gene Organism Category Pfam pChEMBL Type Source
P36888 FLT3 Homo sapiens Human PF00047 PF07714 7.6 Ki ChEMBL
P06213 INSR Homo sapiens Human PF00757 PF17870 PF07714 PF01030 7.4 Ki ChEMBL
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 6.7 Ki ChEMBL
P08069 IGF1R Homo sapiens Human PF00757 PF07714 PF01030 6.7 Ki ChEMBL
P51451 BLK Homo sapiens Human PF07714 PF00017 PF00018 6.7 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.6 Ki ChEMBL
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 6.5 Ki ChEMBL
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.4 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.0 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.0 Ki ChEMBL
P07333 CSF1R Homo sapiens Human PF00047 PF25305 PF07714 6.0 Ki ChEMBL
P10721 KIT Homo sapiens Human PF00047 PF07714 6.0 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.0 Ki ChEMBL