N-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-2-((2-(methylamino)pyrimidin-4-yl)methylamino)benzamide

InChIKey	`LRUKBEHTGXFIJS-UHFFFAOYSA-N`
Compound Name	N-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-2-((2-(methylamino)pyrimidin-4-yl)methylamino)benzamide
Canonical SMILES	`CNc1nccc(CNc2ccccc2C(=O)Nc2ccc3c(c2)OC(F)(F)O3)n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.52
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P10721	KIT	Homo sapiens	Human	PF00047 PF07714	8.5	IC50	ChEMBL;BindingDB
P15056	BRAF	Homo sapiens	Human	PF00130 PF07714 PF02196	8.5	pIC50	TTD_MultiTarget