N-{3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-1-methyl-prop-2-ynyl}-N-hydroxy-acetamide

InChIKey	`LRGIPQJRKVRNOS-UHFFFAOYSA-N`
Compound Name	N-{3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-1-methyl-prop-2-ynyl}-N-hydroxy-acetamide
Canonical SMILES	`COc1ccc(-n2nc(C#CC(C)N(O)C(C)=O)cc2-c2ccc(Cl)cc2)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.33
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P23219	PTGS1	Homo sapiens	Human	PF03098	7.5	IC50	ChEMBL
P35354	PTGS2	Homo sapiens	Human	PF03098	7.5	IC50	ChEMBL;BindingDB
P09917	ALOX5	Homo sapiens	Human	PF00305 PF01477	7.0	IC50	ChEMBL;BindingDB