Molecule Details
| InChIKey | LQYNONCEAYAGNN-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-(4-chlorophenyl)-N-[3-methyl-8-(propan-2-ylamino)-1,2,4,5-tetrahydro-3-benzazepin-7-yl]benzenesulfonamide |
| Canonical SMILES | CC(C)Nc1cc2c(cc1NS(=O)(=O)c1ccc(-c3ccc(Cl)cc3)cc1)CCN(C)CC2 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.2 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P28223 | HTR2A | Homo sapiens | Human | PF00001 | 8.8 | Ki | ChEMBL |
| P35462 | DRD3 | Homo sapiens | Human | PF00001 | 8.5 | Ki | ChEMBL |
| P28335 | HTR2C | Homo sapiens | Human | PF00001 | 8.3 | Ki | ChEMBL |
| P50406 | HTR6 | Homo sapiens | Human | PF00001 | 8.1 | Ki | ChEMBL |
| P14416 | DRD2 | Homo sapiens | Human | PF00001 | 7.3 | Ki | ChEMBL |