Molecule Details
| InChIKey | LQSTXUKGXUCNPL-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-(11-Cyclopropyl-10-oxo-1,6,11-triazatricyclo[7.4.0.02,7]trideca-2(7),3,5,8,12-pentaen-8-yl)benzonitrile |
| Canonical SMILES | N#Cc1ccc(-c2c3ncccc3n3ccn(C4CC4)c(=O)c23)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.04 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 8.6 | IC50 | BindingDB |
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 8.6 | IC50 | ChEMBL;BindingDB |
| Q08493 | PDE4C | Homo sapiens | Human | PF18100 PF00233 | 8.1 | IC50 | BindingDB |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 7.0 | IC50 | BindingDB |