Molecule Details
InChIKeyLPNSUJMINOXWJC-UHFFFAOYSA-N
Compound Name4-[4-(4-fluorophenyl)-5-(4-pyridyl)-1H-imidazol-2-yl]benzoic acid
Canonical SMILESO=C(O)c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL6.54
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
Q16539 MAPK14 Homo sapiens Human PF00069 7.6 IC50 ChEMBL;BindingDB
P36897 TGFBR1 Homo sapiens Human PF01064 PF00069 PF08515 6.4 IC50 ChEMBL;BindingDB
O15264 MAPK13 Homo sapiens Human PF00069 6.3 IC50 ChEMBL
P53778 MAPK12 Homo sapiens Human PF00069 6.3 IC50 ChEMBL
Q15759 MAPK11 Homo sapiens Human PF00069 6.3 IC50 ChEMBL
P09917 ALOX5 Homo sapiens Human PF00305 PF01477 6.3 IC50 ChEMBL;BindingDB