2-(3,4-dimethoxyphenylthio)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine

InChIKey	`LPIMYXVAEGCNPJ-UHFFFAOYSA-N`
Compound Name	2-(3,4-dimethoxyphenylthio)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine
Canonical SMILES	`COc1ccc(Sc2nc(Nc3cc(C)[nH]n3)c3ccccc3n2)cc1OC`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.49
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O14965	AURKA	Homo sapiens	Human	PF00069	7.8	Ki	ChEMBL;BindingDB
O75716	STK16	Homo sapiens	Human	PF00069	7.8	pIC50	TTD_MultiTarget
Q96GD4	AURKB	Homo sapiens	Human	PF00069	6.9	Ki	ChEMBL;BindingDB